You can use the Webflow CMS API to add, update, delete, and publish content to you content hosted using the Webflow CMS - developers.webflow.com 
Webflow looks a good solution to design responsive CSS that we can publish wiki content to. However it is relatively expensive, and there is currently no static site export for content stored in the CMS. This limits the long term utility of using the Webflow CMS API to store and publish content to.
The Webflow CMS API while not allowing you to create sites, domains, or collections does allow control over item creation and deletion:
- Get All Items For a Collection - Get Single Item - Create New Collection Item - Create New Live Collection Item - Update Collection Item - Remove Collection Item